Evolving friendships and shifting ethical dilemmas: fieldworkers' experiences in a short term community based study in Kenya.

by Dorcas Kamuya, Sally Theobold, Patrick K Munywoki, Dorothy Koech, Wenzel P Geissler, Sassy Molyneux

In this paper, we draw on qualitative observation and interview data collected alongside a six month basic science study which involved a team of FWs regularly visiting 47 participating households in their homes. The qualitative study documented how relationships between field workers and research participants were initiated, developed and evolved over the course of the study, the shifting dilemmas FWs faced and how they handled them. 

23rd March 2018 • comment

Research Involving Health Providers and Managers: Ethical Issues Faced by Researchers Conducting Diverse Health Policy and Systems Research in Kenya.

by Sassy Molyneux, Benjamin Tsofa, Edwine Barasa, Mary Muyoka Nyikuri, Evelyn Wanjiku Waweru , Catherine Goodman, Lucy Gilson

The authors examine the ethical issues that arose for researchers over the course of conducting three HPSR studies in Kenya in which health managers and providers were key participants. 

23rd March 2018 • comment

Conducting good, ethical global health research is now more important than ever. Increased global mobility and connectivity mean that in today’s world there is no such thing as ‘local health’. As a collection, these stories offer a flexible resource for training across a variety of contexts, such as medical research organizations, universities, collaborative sites, and NGOs. 

12th November 2017 • comment

This book is a collection of fictionalised case studies of everyday ethical dilemmas and challenges, encountered in the process of conducting global health research in places where the effects of global, political and economic inequality are particularly evident. 

23rd November 2016 • comment

The Good Clinical Practices (GCP) codes of the WHO and the International Conference of Harmonization set international standards for clinical research. But critics argue that they were written without consideration for the challenges faced in low and middle income countries (LMICs).

17th November 2016 • comment
11th November 2016 • comment

Around half of the clinical trials done on medicines we use today are not published; a tragic truth that needs to be changed.

24th October 2016 • comment

Today,The Global Health Network launches Mesh: a new online platform co-created by its users and aiming to improve Community Engagement with health in low and middle income countries.

20th September 2016 • comment

Informed consent is vital in clinical research. Achieving adequate comprehension in low literacy settings however is a significant challenge.

26th July 2016 • comment

This study highlights the utility of rapid ethical assessment prior to clinical trials involving complex procedures and concepts.

23rd March 2016 • comment

Recent calls have been made for rapid and responsible sharing of research data in public health emergencies and outbreaks.

8th February 2016 • comment

New guidelines help researchers undertaking systematic reviews and IPD meta-analyses to report their findings in a full and transparent manner.

13th July 2015 • comment

Understandings of genomic research in developing countries: a qualitative study of the views of MalariaGEN participants in Mali

by Karim Traore, Susan Bull, Alassane Niare, Salimata Konate, Mahamadou A. Thera, Dominic Kwiatkowski, Michael Parker, Ogobara K. Doumbo

Obtaining informed consent for participation in genomic research in low-income settings presents specific ethical issues requiring attention. These include the challenges that arise when providing information about unfamiliar and technical research methods, the implications of complicated infrastructure and data sharing requirements, and the potential consequences of future research with samples and data.

7th July 2015 • comment

We have recently obtained permission to share some very interesting videos on The Global Health Network. The videos are from Global Health Videos by Greg Martin. You can follow more videos from him at his YouTube channel. This series of videos deal with Glolbal Health and Ethics.

2nd June 2014 • comment

This article, published in AIDS & Clinical Research, reports on a project aiming at building the capacity of regulatory agencies in Nigeria.

22nd January 2014 • comment

Managing Incidental Genomic Findings in Clinical Trials: Fulfillment of the principle of justice

by Rafael Dal-Ré, Nicholas Katsanis, Sara Katsanis, Lisa S. Parker, Carmen Ayuso

Genome/exome data are likely to play an increasing role in clinical trials, and incidental findings are likely to be viewed as potential benefits for individuals of research participation.

15th January 2014 • comment

Research misconduct is a global problem as research is a global activity. Wherever there is human activity there is misconduct, but we lack reliable data on the extent and distribution of research misconduct. This PLoS paper seeks to illustrate some examples of researsch misconduct in LMICs.

3rd April 2013 • comment

Community engagement is increasingly promoted to strengthen the ethics of medical research in low-income countries. One strategy is to use community advisory boards (CABs): semi-independent groups that can potentially safeguard the rights of study participants and help improve research. However, there is little published on the experience of operating and sustaining CABs.

12th March 2013 • comment

This guidance article aims to provide a fully comprehensive, pragmatic guide for researchers of all roles, but especially ethics reviewers, to explain the details of each type of ethics review. The article is available in English, Spanish, Portuguese and Chinese, and has been kindly provided by www.ctmagnifier.org.

1st January 2013 • comment

Assessing the quality of informed consent in a resource-limited setting: A cross-sectional study

by Ronald Kiguba, Paul Kutyabami, Stephen Kiwuwa, Elly Katabira, Nelson K Sewankambo

The process of obtaining informed consent continues to be a contentious issue in clinical and public health research carried out in resource-limited settings. We sought to evaluate this process among human research participants in randomly selected active research studies approved by the School of Medicine Research and Ethics Committee at the College of Health Sciences, Makerere University.

6th September 2012 • comment

Are students kidding with health research ethics? The case of HIV/AIDS research in Cameroon

by Nchangwi S Munung, Godfrey B Tangwa, Chi P Che, Laurent Vidal, Odile Ouwe-Missi-Oukem-Boyer

Universities in Cameroon are playing an active part in HIV/AIDS research and much of this research is carried out by students, usually for the purpose of a dissertation/thesis. Student theses/dissertations present research findings in a much more comprehensive manner and have been described as the stepping-stone of a budding scientist's potential in becoming an independent researcher. It is therefore important to verify how students handle issues of research ethics.

15th August 2012 • comment

Clinical trials in India continue to be in the news, unfortunately a fair bit being negative coverage.

25th May 2012 • comment

This bibliography is a work in progress and is regularly revised. We are currently updating it to link to any listed papers that are available via open access. If there are papers we're missing, or if you have other comments, please let us know by writing to info@globalhealthbioethics.org.

2nd April 2012 • comment

Abstract Guidance requires that consent processes for research be appropriately tailored to their cultural context. This paper discusses the use of rapid assessments to identify cultural and ethical issues arising when explaining research in studies in The Gambia and Ethiopia.

28th February 2012 • comment

One fundamental ethical principle underpinning research ethics is that of respect for persons. It requires that researchers respect research participants’ autonomy, interests, and wishes, and act on the presumption that participants are the best judges of what their interests are (Nuffield Council on Bioethics 2002). This presumption obliges us to design consent processes for research that facilitate prospective participants’ free and informed decisions as to whether or not to participate in a study.

21st February 2012 • comment

This is the Report from the "Consent to and Community Engagement in Health Research" workshop, which took place between 28 Feb - 03 Mar 2011 in Kilifi, Kenya. The workshop built upon an emerging collaboration between the Ethox Centre in Oxford, the Social and Behavioural Research Group at the Wellcome-KEMRI Unit in Kilifi, the Liverpool School of Tropical Medicine and the Mahidol - Oxford Tropical Medicine Research Unit in Thailand.

1st August 2011 • comment

Many of the scandals that surround modern medicine involve research conducted on human subjects. Consequently when discussion turns to the ethics of research, such atrocities as the Nazi hypothermia experiments at Dachau conentration camp during World War Two (Berger 1990) or the Tuskegee Syphilis Study in Alabama beginning in the 1930s (Pence 2000) are never far from the surface...The reaction to these atrocities has, justifiably, been extreme. In this paper, Sheehan considers the consequences of these reactions - the exclusion of particular groups from participation in research.

21st June 2011 • comment

Ethics in global health research

by M. Parker, S. Bull

This articles explores some of the ethical issues arising in the context of collaborative global health research networks involving partners in developing and developed countries.

11th February 2011 • comment